API (active pharmaceutical ingredients) production typically uses a synthesis process, encompassing raw material storage, dispensing, and charging into reactors, followed by dryings steps using filter dryers, centrifuges, or vacuum dryers. The product is then conveyed, micronized, dispensed, and packed off. These steps normally require secure containment, depending on the nature of the API, using isolators, powder transport systems, and adapted valves.
Healthcare reforms, patent expiries and increased service requirements are forcing pharmaceutical companies to adapt their business models. All pharma companies are facing a new landscape that includes challenges such as meeting complex regulatory legal frameworks, increased market competitiveness, higher containment requirements for more potent APIs, as well as demands for multi-purpose processes, lean production methods, and decreased maintenance costs.
Together with well-established partners, Thurne can supply the right high-quality process equipment for material handling solutions, equipment for dispensing, and complete process lines. This includes contained discharge, filling, conveying, dosing, mixing, dispensing, sampling, micronizing, milling, sieving, granulation, and pack off equipment. All equipment is designed for high containment applications and follows the cGMP standards.