Filter Module (FILTRODISC BIO SD)

Cell separation of cell broth in biotech applications is frequently performed through centrifugation in technical dimensions or with membrane filters in lab scale applications.

Share

The particle load in cell broth is too high for an efficient cell separation with membranes when it comes to technical dimensions. Scale up of membrane filtration is not practical. Centrifugation, an application in which mechanical stress is applied to cells, increases the turbidity through fine particles which have to be removed further downstream the separation and purification process. Alluvium filtration is a well-established method in pharmaceutical industries. Until recently, however, it has not been used for cell separation as it was unavailable as a scalable and disposable solution with all validation requirements.

FILTRODISC™ BIO SD comprises a filtration system that removes cell particles and other turbid matter from a fermentation broth. This system is completely disposable, meaning all material that comes in contact with the product is meant for single-use and can be disposed of after the filtration is completed. This <<disposability>> or <<single use>> reduces cross-contamination risks and cleaning validation efforts, making this method the ideal choice for contract manufacturers (CMO) and other operations with a high frequency of product change. The system is scalable from lab size to industrial size filtration. The transfer from the method development stage to large-scale processes can be easily achieved.

Brand

FILTRODISC BIO SD

Supplier

If you have any questions please don`t hesitate to contact Thurne specialist directly:

Thurne Denmark

CEO M.Sc. Process Engineering & Industrial Economics

Phone number

Mobile phone: +358 40 183 5870

Thurne Finland

Rolf Sundström
Product Sales Manager
Product Sales Manager B.Sc. Automation

Phone number

Mobile phone: +358 45 110 2337

Thurne Sweden

Rolf Sundström
Product Sales Manager
Product Sales Manager B.Sc. Automation

Phone number

Mobile phone: +358 45 110 2337